Children born in eco pros and cons. When eco is not the only way out? High probability of birth of a healthy child

Artificial fertilization occurred not so long ago, but thanks to him, the fate of a large number of fruitless families changed dramatically. Some consider eco to be the only way in treating infertility. But if there is advantages, there are pros and cons of Eco.

pros

Naturally, the first advantage is the productivity of the procedure. Today, more and more children are born thanks to this method.

The pregnancy period and the process of childbirth passes in the same way as after standard fertilization. If one of the spouses is infertile, the extracorporeal fertilization will help in treating infertility.

Experts argue that the biological material is carefully examined, so the child is born healthy. Children are born healthy, they do not differ from their Christmas on physical and mental development. Married couples pay attention only on the benefits of Eco and do not want to know about the various disadvantages of the method.

It is always worth hoping for the best result, then exactly everything will be safely. If Eco is the only chance to have baby and other options are absent, then you do not need to cheat yourself and thereby create problems. In this case, only stupid think about potential problems. The main advantage of Eco is that the chance to get pregnant only increases, and does not decrease.

Cons of the procedure

The method of artificial fertilization is not sufficiently studied, as well as he is young. Scientists of Sweden say that children who have emerged using Eco are subjected to malignant tumors. In addition, such children do not have their children in the future. If the family has a small level of income, then it cannot afford this method, and this is a significant minus.

Eco success is the third part of statistics. It should be understood that when the embryos are sitting in the uterus, then this is not always harmless to the health of a woman - these are disadvantages of Eco.

There is an ectopic pregnancy, allergies, the work of the stomach and intestines is disturbed. Consequently, partners will pre-examine and confirm the diagnosis.

Frequent are cases of multiple pregnancy. Not everyone wants to have two children at once, so when extracting extra embryos, the likelihood of miscarriage increases. Repeated procedure is carried out three to five years.

During this period, the balance of hormones is restored. But there is a possibility not to wait so much time, then the embryos are frozen and after six months they are again sitting, if there was an unsuccessful attempt. It has not yet been studied why children after eco are born with defined vices. Pathology is not dangerous, with the help of surgical intervention, they are getting rid of them.

Thus, the minuses of the ECO procedure are essential, so the married couple must take everything to avoid them.

Ethical side

If you look at the ethical aspects of artificial fertilization, it is difficult and ambiguous. Bioethics is engaged in the study of the moral side of the work of people in the medical sphere. Ethics considers human moral behavior. Eco brings humanity, both blessing and harm. Indeed, thousands of pairs have become truly happy. But reproductive technologies are interference in the natural birth of a new life. It is rude, threatens spirituality and morality in society.

Today it is an automatic technology, but its success depends on qualified specialists. We are talking about the status of the embryo, the ability to dispose of them. Therefore, eco-eco problems arise.

Saving and getting rid of embryos. Ripen about 20 eggs that are fertilized in the tube. But in the female body implanted one or two embryos. The remaining dying, to be destroyed or for canned if parents wish.

Delete embryos. Medicine looks at it, as an abortion, which is considered a standard procedure. But it can be perceived as murder. When a woman agrees to remove embryos, it is psychological trauma for it.

Bioethic problems associated with extracorporeal fertilization are systematically considered in the field of medicine. It happens at conferences, publications, but until today's unambiguous answer. At the legislative level, Eco's ethical problems are also not resolved.

Thus, the extracorporeal fertilization is considered the only method in the fight against infertility. Everyone wants to have a native child, so if the tools allow, married couples try to conceive the baby with artificial fertilization. Despite all the disadvantages of Eco, most couples are ready to give birth and become happy parents.

Eco as a method of combating infertility

Extracorporeal fertilization (ECO) is the main method of treating infertility, by auxiliary reproductive technologies. Unfortunately, the growth of fruitless marriages in Russia is noticeably growing, combining both female and male form of infertility. It is almost impossible to identify the objective causes of this pathology, one can only assume that these changes can occur on the background of poor-quality food, ecology, lifestyle and other aspects.

But, fortunately, modern medicine is quite successfully fighting with various forms of infertility by the method of extracorporeal fertilization (ECO). Eco-protocol statistics at this time are very positive.

Since 1978, couples who wish to become parents, but who for some reasons do not get to realize this in reality, there has been a chance to fulfill this dream.

This chance - Eco fertilization. If earlier Eco was considered an exclusive procedure, now, each modern clinic can offer the method of extracorporeal fertilization of the needy pair.

Everything else, thanks to Eco, the women of the age category also got a chance to have a child. Thus, after this procedure, a prosperous pregnancy and successful birth of thousands of age-related women occurred. Eco after 40 years in our time is far from uncommon, success for successful conception is significantly falling compared with younger women, but the chances are decent.

History of extracorporeal fertilization

The history of the emergence of Eco begins back in 1944. Hamilton from the United States begins the first attempts to fertilize eggs outside the body, but his attempts were not crowned with success. In the same year, Rock, Minkin after more than 500 attempts, in three cases they received crushed eggs to stage 2 of blastomers.

Only after 7 years, M.C. Chang begins to develop media cultivation media and human embryos outside the body. In 1966, Robert D. Edwards found that the ripening of eggs in women occurs 36 hours after the peak of LH in the body, later for this discovery he received the Nobel Prize.

The first eco pregnancy in the world turned out in 1973, thanks to the group of scientists led by Karl Wood. But, unfortunately, the fertilized egg cell was soon rejected by the body of the uterus naturally. In 1983, the same scientist managed to achieve the appearance of an infant developed from a frozen embryo.

The first successful ECO procedure was produced in the UK in 1977. As a result, Louise Brown was born in 1978. The first successful use of ECO in Russia was carried out in 1986 in Moscow, as a result of which a girl appeared also on the world.

From these times, embryology begins to explore groups of scientists from these times in Russia. By 1990, there were more than 20 thousand children concerned in the tube.

Now the most extensive country for the use of extracorporeal fertilization is Israel. About 3.5 thousand ECO procedures in Israel accounted for 1 million inhabitants per year.

Science in the field of Reproductology moves forward, now in addition to Eco, doctors will successfully apply the ICSI method and pre-impalance diagnostics for needy steam.

How is the procedure of eco

About how Eco makes, not little video and documentaries are removed. But you can tell in a few words about the main stages and describe how Eco is happening. Eco - represents a procedure in which female egg female eggs is happening outside the body (Invitro). The cultivation of embryos up to a certain day is carried out in a test tube with special, biological environments. After that, the embryo is sitting in the cavity of the woman's uterus. To do this, it is necessary to extract the eggs of a woman and the sperm of the man, to carry out fertilization and transfer the embryo to the uterine cavity.

Scheme of extracorporeal fertilization

The ECO procedure consists of several stages. The first thing that the doctor does before joining the program, will appoint a full-fledged pair survey to establish the need and feasibility of this procedure. Then, for a woman individually, based on the age and survey results, the doctor selects the most appropriate scheme of the stimulation of supersuvulation, which in turn will ensure the collection of not one, and several eggs. Then there is a puncture of follicles for collecting eggs and collect sperm of a man. In the tube, the embryologist exercises cell fertilization, and the embryos cultivation in special environments occurs within 2-6 days. The final stage of the Eco cycle is the transfer of embryos to the cavity of the woman. All stages of ECO occur under the watchful observation of highly qualified specialists in the field of reproductive medicine: reproductologists, andrologists, embryologists. At each reception, the reproductist should tell about how ECO passes, its main moments and features of the patient.

Stimulation of ovulation in eco protocols

Almost every Eco procedure passes with the stimulation of supervision. This is necessary so that the woman is ripe not alone, but a few eggs. Thus, stimulation with ECO increases the chance to safely fertilize and obtain viable embryos. Ovulation stimulation schemes are different, and depend on the age and reserve of the woman's eggs. Stimulation occurs under the action of hormonal drugs.

To stimulate ovulation, they use both direct inductors that contain the hormone of FSH and indirect, stimulating the hypophies produce this hormone.

Here are some drugs for Eco:

"Klostilbyt" - enhances the secretion of gonadotropins (FSH - follicle-stimulating hormone, LG - luteinizing hormone);
"Menogon" - Horodotropin, which contains LG and FSH. This drug increases the concentration of sex hormones in plasma, due to which the growth of ovaries and ripening of follicles increases. Also stimulates the growth of endometrial;
"Pureregon" - the drug has an estrogen-like action, with which the concentration of FSH increases, which in turn stimulates the development of the set of follicles and synthesis of steroids;
"Menopour" is a drug of menopausal human gonadotropin (FSH: LG \u003d 1: 1). It causes an increase in the concentration of estrogen in the blood, growth and ripening of follicles and endometrial;
The "Permgery" is a combined drug containing a recombinant follicle-stimulating hormone (FSH) of a person and a recombinant luteinizing hormone (LH) of a person in a 2: 1 ratio. Stimulates the growth and ripening of follicles and endometrial.

Ovulation stimulation usually begins with 2-5 days of the menstrual cycle, but it happens that from 21, then such protocols are called "long". In such protocols, agonists are used before stimulation, drugs blocking hypophysis on the production of sex hormones, then a scheme of stimulation by gonadotropins. This protocol is suitable for women with low AMG and the age group after 30, as it causes more ripening of follicles.

At the end of the stimulation, the drugs of chorionic gonadotropin (HCG) are used, which completes the ripening process of eggs.

It is worth remembering that the whole process proceeds under the strict observation of the attending physician.

Puncture of follicles in Eco Protocols

The next stage of the treatment of infertility by the ECO method is the puncture of follicles. With the help of it collecting matured eggs. The puncture of follicles with ECO, as a rule, is carried out under a short-term general anesthesia, 34-36 hours after the introduction of hCG. With the help of a special needle, the trans vaginal method, through the puncture in the wall of the vagina, the doctor punctures the follicles for the withdrawal of eggs. With the help of suction, the contents of the content of the follicle along with the egg cell are made. The whole procedure is under the control of ultrasound.

Puncture of follicles with ECO requires its preparation. So, as this is an invasive procedure, on the eve, it is advisable to free the intestines, and come on an empty stomach.

After the procedure, pulling pain at the bottom of the abdomen and not abundant bleeding is possible. If the pains do not pass and even enhance, you must immediately contact the clinic where the procedure was performed.

On the day of puncture, the follicles is carried out and the collection of sperm of her husband, except in cases where the frozen material is used.

Egg fertilization of egg and cultivation of embryos

A very important stage in the ECO cycle is the fertilization of the withdrawn eggs with spermatozoa. After the follicle puncture, the embryologist launders the eggs of a woman from the contents of the follicle and calculate the wealthy cells. Then, after special processing of men's sperm, part of the spermatozoa is placed in a tube with an egg, where fertilization occurs.

Fertilized cells (zygotes) begin to share. The cultivation of embryos, that is, the process of the development of embryos outside the body, and in special environments, occurs from 2 to 5 days, not counting the day of puncture. At this time, the embryologist assesses the state of embryos and their viability.

Embryo Subject in the uterine cavity

The cultivating moment of ECO protocols is a fox of embryos into the cavity of a woman's uterus. Preparation for the transfer of embryos with ECO lies in therapy aimed at improving the readiness of the endometrial, the mucous membrane of the uterus. It is taken into account both the size and structure of the endometrial, which are adjusted by the reception of progesterone containing drugs. As a rule, embryos transport are carried out once, in the stage of eight cellular embryo or blastocysts. But also, there is a double-transfer practice.

The transfer of embryos with eco, an absolutely painless procedure, which is carried out using a special catheter and a syringe. The catheter is introduced into the cervix and when the rod is pressed, the embryos are entered into the cavity.

After transferring embryos, it follows a while in a horizontal position. Many women are worried about this procedure, as the transfer of embryos is a very important stage of all Eco. Do not worry about the fact that embryos can leave the cavity, pour or fall out, it is impossible. The implantation of embryos after eco is happening in the same way as in the natural cycle for 6-10 days after ovulation or puncture.

After the fastener of embryos, the doctor prescribes support to drugs that need to be taken to the results of HCG, usually waiting time for two weeks. Pregnancy after Eco proceeds the same as the pregnancy that has occurred naturally, for the exclusion of unagreering moments of a woman's diagnosis.

Pros and cons of eco

Undoubtedly, artificial fertilization (ECO) has a chief plus, for whom many couples are ready to go to all are a chance to have a child. Despite the fact that Eco's effectiveness is high enough, it is not necessary to consider it as a panacea in treating infertility. The effects of eco can be different, and sometimes, threaten the patient's life. This procedure should have its own testimony.

The main disadvantages of Eco:

syndrome of ovarian hyperstimulation (SGA);
multiple pregnancies;
inaccessibility of the procedure because of great cost.

In addition, hormonal therapy is not transferred to all women equally easily, it is a huge burden on the body that requires its preparation. That is why the question of how many times you can do Eco for each pair remains individual. It depends on the age, the state of health of the reproductive sphere and the body as a whole.

Indications and Contraindications to Eco

Eco fertilization, like any invasive procedure, has its own testimony and contraindications that the doctor is guided by offering an infertile pair this program.

Main readings to Eco:

pathology of uterine pipes, or their absence;
pathology of the cervical canal;
immunological infertility;
unsuccessful treatment, throughout the year endocrine infertility (, diseases of the pituitary gland, adrenal glands, thyroid gland, diabetes mellitus);
unsuccessful treatment, during the year;
mixed infertility factors observed during the year;
oligostenozoospermia;

Also, the indication to Eco may become infertility of unclear genes, confirmed after one year.

Basic contraindications to Eco:

congenital or acquired pathology of the uterine cavity (for example);
congenital genetic anomalies (birth in the history of children with defects of development);
psychological and somatic deviations that prevent the baby tooling;
serious hereditary diseases.

Unfortunately, at present, more and more marital couples cannot conceive a child themselves. Medicine comes to help such pairs, in particular, the method of extracorporeal fertilization method, or Eco. The essence of Eco is reduced to the receipt of a mature egg from a woman, fertilizing her male spermatozoa, getting the embryo and adding it to a woman's uterus. The ECO method received a wide resonance among public opinion, today we will look at the arguments in favor of both the ECO method.

Pluses of Eco

Of course, one of the advantages of this method can be called its productivity - more and more children are born, thanks to this method. Pregnancy and childbirth women proceed in the same way as with natural fertilization. In addition, according to the doctors of gynecologists and genetics, the biological material is subjected to a thorough medical examination, thereby significantly decreases the risk of birth of children with hereditary and genetic diseases.

For the first time, the method of extracorporeal fertilization was used in the UK, in 1978, and in Russia the first child on Eco was born in 1986

Cons of the procedure

This method of fertilization is relatively young and not well understood. In particular, Swedish scientists believe that children born using Eco are more susceptible to malignant neoplasms. In addition, there is an opinion that children born in this way themselves have problems with confusion. The high cost of this method makes it inaccessible for families with a small wage level.

The treatment procedure and fertilization takes a long time - from a few weeks to one month. All this time, a woman needs to take tests every day and undergo additional surveys.

The risk to the health of a woman is also not excluded. It lies not only in the reception of hormonal drugs, but also in the fact that during seizures the bleeding can open, it is possible to get infections. Also, with an incorrect implacation of the embryo, there is a risk of developing ectopic pregnancy.

During a long procedure of fertilization, some women occur the nervous disorders - psychosis, attacks of aggression and panic.

True and myths about the method (video)

An experienced doctor Gynecologist-Reproductist Oksana Gaivoronskaya will tell the audience about the extracorporeal method of fertilization and will answer the most asked questions about Eco.

Despite all the disadvantages of the eco method, he is gaining increasing popularity. For many, he remains the only hope of a child. However, if you fail to conceive a baby, do not rush to immediately do Eco, you may be able to eliminate the cause and you can get pregnant yourself - you will definitely consult with the gynecologist-reproductologist.

For married couples who cannot independently conceive a desired child, Eco procedure sometimes becomes the only chance to become parents. Let's deal with the fact that it is a method of extracorporeal fertilization.

What is the essence of the method?

When the ECO procedure, fertilization occurs in a test tube, after which the embryo is carried out in the Women's Mature, or Surrogate Mother. If the procedure has passed successfully and the pregnancy has come, it is likely that several embryos arrive at once and then pregnancy is considered multiple. If a woman does not want to lower several kids at once, then in the early period of pregnancy, the embryo reduction is carried out, that is, unnecessary zygotes are withdrawn. However, deciding to the reduction method, the woman should understand that it can lead to the death of other embryos in the uterus and the subsequent miscarriage.

In general, according to statistics, the success of the ECO procedure is 35%. If a woman appeals to the doctor for the first time, the doctors try to spend eco with minimal stimulation, which is most closely close to the natural fertilization process.

When is the need for artificial fertilization?

The ECO method is highly efficient in cases where it is impossible to eliminate the cause of the family couple's infertility, which prevents independent conception. Such reasons may be an ectopic pregnancy, in which a woman remove the uterine tube, as well as various inflammatory gynecological diseases, which lead to ovulation disorders.

Sometimes the independent conception of the child is impossible due to the insufficient amount of sperm in a man. In this case, an andrologist (a doctor engaged in the reproductive health of men) receives men's sperm by puncture, or surgery. Of course, you can simply introduce the resulting cum into the vagina to a woman, but the Eco method in this case gives more chances to the successful occurrence of pregnancy.

Procedure course

The figure below shows the conditional scheme of the method of extracorporeal fertilization.

1. Puncture and fence of eggs after stimulation of ovulation. 2. Fertilization in the test tube. 3. Transfer of embryos to the uterine cavity.

Stimulation of fertilization

Before conducting the eco, the woman's body is stimulated by hormonal drugs that help to contemplate several eggs at once. This is a necessary condition, since for a successful substrate you need to have several embryos. On average, the stimulation continues for about 14 days, in which a woman herself makes itself an injection for the skin.
After stimulating the body hormones, the woman outpatiently spends the follicle puncture to extract the ripened eggs. It does not painfully hurt, since the procedure is small-acting.

Before conducting the ECO, dine-relinged injections are prescribed. This drug is used to stimulate ovulation when introducing a minimum dosage of 0.1 mg subcutaneously. Derencelyine is administered under the skin from 2 days of the menstrual cycle of 1 injection per day.

Diffelin injection must also be made for 2-3 days after the transfer of the embryo from the test tube to the uterus. It is necessary to mute the production of own hormones so that no body hyperimulation occurred. After the injection of diffelin, a woman can have minor pain in the lower abdomen, this is normal.

Another drug for successful implantation of the embryo is pyroxics. The tablet needs to drink an hour before the fetal egg pin. Pyroxikov increases the chance of successful embryo in the uterus cavity. In addition, the pyroxiks improve blood supply to the small pelvis organs, which can also contribute to the successful embryo attachment after transferring from the test tube to the uterus.

ECO procedure

The artificial conception procedure is carried out in the embryological laboratory with a highly qualified specialist. For connecting sperm and eggs, modern equipment uses modern equipment. The fusion of cells is performed in a special solution. A few days after the fusion of the genital cells, the embryos are ready, and you can go to the next step.

Before transferring the embryo to the uterine cavity, the embryologist conducts a thorough study of the resulting gamete. Thanks to modern methods of medicine, it is possible to explore the state of the embryo consisting of only 4 cells. With the help of special procedures, congenital developmental abnormalities, chromosomal diseases, hemophilia and other pathologies incompatible with life can be identified.

Next, after the selection of the highest quality embryos, the zygota is transferred to the uterus cavity. The fox of the embryo is performed using a special elastic catheter, it absolutely does not hurt. After the embryo prodigation, a woman can continue to lead a normal lifestyle, that is, no special conditions do not need to be observed. Exceptions are only physical stress and psychological stress.

Pregnancy and childbirth

Pregnancy as a result of Eco occurs in 35% of cases. After the fastener of embryos in the uterus, it is necessary to constantly control the growth of the HCG hormone level. 14-18 days after the transfer, a woman can do a pregnancy test. Upon the occurrence of multiple pregnancy, the reduction is to be resolved, since it is much harder to get several fruits at once than one.

Childbirth after artificial fertilization are no different from those that have come as a result of the natural conception of conception.

Eco can only be done after a complete examination of both spouses, identifying the cause of infertility, and evaluating the state of the reproductive system of women.

How often can I use the ECO method?

The ECO procedure cannot be used often due to a variety of reasons. Many patients can not afford the fertilization of "in a test tube" due to the great value of the procedure. Also, the rate of ECO method is limited due to the hyperstimulation of the female organism for the production of egg cells. The re-conducting of ovulation stimulation is possible only after 2.5-3 years, after the complete restoration of the hormonal balance of the body.

Eco is a fairly safe method of occurrence of desired pregnancy, but the success of conception from the tube largely depends on the individual characteristics of the body. On some women everything turns out the first time, and another attempts are not enough. The number of attempts by ECO determines the doctor. With repeated artificial fertilization, the use of previous embryos, which remained in the embryology center. You can repeat the shock in 6 months after 1 unsuccessful embryo substrate.

Complications after eco

The minuses of fertilization "in the tube" is multiplot. Doctors face this factor most often. Also, the most frequent complication is the need for the reduction of "extra" embryos that subsequently can lead to miscarriage. Another disadvantage of Eco is the ovarian hyperstimulation syndrome, as a result of the complication of hormonal therapy.

Probably the main minus of artificial conception is the cost of the procedure. Eco is about 10 thousand dollars. Pay such an amount for the fertilization procedure in the test tube may not have every family that dreams of baby. The cost of Eco does not include the amount of drugs for the overtimulation of the ovaries, their woman should buy independently.

As a result, for many family couples, any opportunity to experience the joy of parenthood and have a chance to have their own child, often outweighs all possible cons and complications after Eco. We wish you successful procedures and easy childbirth. The most important thing is healthy kids!

Content:

In the practice of extracorporeal fertilization, two protocols are common - short protocol eco and long. They both involve the introduction of the hormonal drugs selected by a specialist. These medicines are needed to stimulate the ovaries and the production of egg cells, which will be fertilized in vitro. Both protocols have differences only before the fence of follicles, and further develop in a single scheme. Although long is considered more common, in certain situations the doctor appoints short protocol. In this article we will deal with the difference between two schemes, as well as what advantages and disadvantages are inherent in short.

Scheme of the short protocol eco

As can be seen from the name for short protocol eco Suggested deadlines. In total, 4 main stages can be distinguished in it:

Stimulation of supervision of hormone therapy;
Fence of follicles with eggs;
Extracorporeal fertilization, incubation of embryos;
Fear of embryos in the maternal uterus.

Lasts short protocol eco About two weeks, in contrast to the long, which takes an average of a month and a half. The start of the short protocol is associated with 3-5 days of the menstrual cycle. At this time, hormonal injections are beginning to put hormonal injections, which cause superstration, that is, the maturation of the sets of eggs ready for fertilization in several follicles.

Initially, the highest doses of drugs are appointed, in the future the doctor reduces their dose. Such a scheme allows you to get eggs in women with a small follicular reserve. During the stimulating phase, in addition to hormone therapy, a regular inspection of a specialist, surrendering blood tests. It lasts this period until puncture, which is usually happening on the 15th day after the start of the stimulation of supervision.

The puncture implies the withdrawal of the eggs, after which they will be selected and fertilized by the sperm of the partner under the microscope. After the ripening of embryos in the incubation conditions of the laboratory, they are planted into the matt of the future mother. Two weeks, the first test for the definition of pregnancy is surrendered - blood test at hormone hong.